Consider the example problem of how to launch photons into a tissue so as to simulate a collimated laser beam distributed spatially as a Gaussian beam. Let the center of the beam be located at r = 0 and the distance from the center of the beam to a point of photon entry be denoted as r. Assume that the beam is a cylindrically symmetric beam around the central z-axis at r = 0. Then the probability density function for photon entry as a function of radial position r is given:
Note that we are considering a cylindrically symmetric 2D Gaussian so one must integrate the Gaussian over the incremental areas composed of annular rings of circumference (2 pi r) and radial width dr: dA = (2 pi r dr). The 2D normalization requires the normalization factor (pi w2). 1D (planar) or 3D (spherical) integrations would require different incremental areas and different normalization factors.
We have learned that we wish to set up the equation
Solve the above equation for r1 as a function of rnd:
Note that -ln(1 - rnd) and -ln(rnd) will sample equivalently because rnd is a random number uniformly distributed over the interval 0 to 1, hence 1-rnd will also be a random number uniformly distributed over 0 to 1. The function sqrt[x] specifies the square root of x, which equals x1/2.
So, our final expression is:
Using this expression, a set of random numbers specifies a set of values r1 such that the histogram of r1 values has the shape of a Gaussian beam as a function of radial position r1 with a 1/e2 radius of w.