Noninvasive monitoring of blood oxygenation by phase-resolved transmission spectroscopy

In a recent optical study two dimensional intensity patterns of light irradiated into suspensions of mitochondria were investigated. We designed our experimental model in such a way that the concentration of scattering particles was similar to concentrations found in tissues of humans and mammals. Earlier measurements performed in isolated and hemoglobin-free perfused rat liver and heart revealed that tissue spectra were strongly altered by light scattering when functional states of the two organs e.g. tissll on the measurements was investigated analytically and with Monte Carlo simulations.

A. H. Hielscher, F. K. Tittel, S. L. Jacques, R. R. Alfano, "Noninvasive monitoring of blood oxygenation by phase-resolved transmission spectroscopy," SPIE Proceedings of Photon Migration and Imaging in Random Media and Tissues, edited by B. Chance, 1888, 275-288 (1993).


Home | Publications

© SAP 5 Dec 1997