Dosimetry of laser fluence rates within a tissue are required for proper planning of photodynamic therapy at a specific site on a given individual. A simple one- dimensional theory of light penetration into tissue is presented. A device for measurement of the total reflectance and the lateral diffusion of light provides a simple means for specifying the tissue optical parameters that govern laser dosimetry. Rules of thumb for complicating factors such as narrow laser beams and optical fiber delivery are discussed.
S. L. Jacques, "Simple theory, measurements, and rules of thumb for dosimetry during photodynamic therapy," SPIE Proceedings of Photodynamic Therapy: Mechanisms, edited by T. J. Dougherty, 1065, 100 (1989).