Mapping radiant energy distributions during laser irradiation of collagen phantoms by photolabeling with tetrabrominated rhodamine

A method is proposed for mapping laser light distributions in gel phantoms by measurement of the distribution of a fluorescent compound that has been photolabeled to the gel by the laser irradiance. A preliminary study of photolabeling by an argon laser using tetrabrominated rhodamine (TBR) was conducted in collagen gel phantoms to illustrate the feasibility of the method. A discussion of the basic quantitative relationships for analysis of measurements is presented.

S. L. Jacques, T. Hasan, "Mapping radiant energy distributions during laser irradiation of collagen phantoms by photolabeling with tetrabrominated rhodamine," SPIE Proceedings of Laser- Tissue Interaction III, edited by S. L. Jacques, 1646, 219-226 (1992).


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