A striking consequence of 248 nm excimer laser irradiation of skin in a stable vivid blue fluorescence easily visulalized under UVA illumination. Its spectral properties (excitation maximum at ˜ 335 nm; emission maximum at ˜ 430 nm) are somewhat similiar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.
D. J. McAuliffe, S. L. Jacques, A. S. Hayes, "Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation," SPIE Proceedings of Laser-Tissue Interaction, edited by S. L. Jacques, 1202, 93-102 (1990).