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Light Transport in Tissue


Inverse method

The concept behind the inverse method described in this chapter is straightforward (Figure 6.1): (a) guess a set of optical properties; (b) calculate the reflection and transmission; (c) compare the calculated values with the measured reflection and transmission; (d) if the calculated and measured values are not equal then repeat the process with a new guess.

Three measurements are required to determine three unknowns. Two possible sets of measurements are the diffuse reflection Rdiffusemeas, the total transmission Ttotalmeas, and the collimated transmission Tcollmathrmmeas, or alternatively, Rdiffusemeas, Ttotalmeas, and the anisotropy of the phase function gHG. The first set requires removal of the integrating sphere assembly in the spectrophotometer and the second set requires an independent measurement of the anisotropy of the tissue with a goniophotometer. In Section 6.1.1 below the uniqueness of the optical properties obtained from such measurements is discussed. Section 6.1.2 contains details of the inversion process.



S. A. Prahl."Light Transport in Tissue," PhD thesis, University of Texas at Austin, 1988.